Which of the following is a boxed warning for JAK inhibitors?

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Multiple Choice

Which of the following is a boxed warning for JAK inhibitors?

Explanation:
Boxed warnings highlight the most serious risks. JAK inhibitors block enzymes (JAKs) that help transmit signals for many cytokines needed to fight infections. This broad immune suppression can lead to serious infections, including TB, hepatitis B reactivation, and other opportunistic infections, which is why a black box warning is set for this class. The other listed effects—hypotension, nausea, and dizziness—are possible side effects but they do not carry the boxed warning.

Boxed warnings highlight the most serious risks. JAK inhibitors block enzymes (JAKs) that help transmit signals for many cytokines needed to fight infections. This broad immune suppression can lead to serious infections, including TB, hepatitis B reactivation, and other opportunistic infections, which is why a black box warning is set for this class. The other listed effects—hypotension, nausea, and dizziness—are possible side effects but they do not carry the boxed warning.

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