Which of the following is a csDMARD example?

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Multiple Choice

Which of the following is a csDMARD example?

Explanation:
Conventional synthetic DMARDs are traditional, non-biologic medicines that modify disease activity by broadly dampening the immune system. Methotrexate is the classic csDMARD used in dermatology (for psoriasis and psoriatic arthritis) and works as an antimetabolite that reduces immune cell proliferation and inflammatory signaling. Infliximab and adalimumab are biologic DMARDs—monoclonal antibodies that neutralize TNF—so they belong to the biologic category rather than csDMARDs. Tofacitinib is a targeted synthetic DMARD, a small-molecule JAK inhibitor that acts on specific signaling pathways rather than broad immune suppression. Therefore, methotrexate is the csDMARD example.

Conventional synthetic DMARDs are traditional, non-biologic medicines that modify disease activity by broadly dampening the immune system. Methotrexate is the classic csDMARD used in dermatology (for psoriasis and psoriatic arthritis) and works as an antimetabolite that reduces immune cell proliferation and inflammatory signaling. Infliximab and adalimumab are biologic DMARDs—monoclonal antibodies that neutralize TNF—so they belong to the biologic category rather than csDMARDs. Tofacitinib is a targeted synthetic DMARD, a small-molecule JAK inhibitor that acts on specific signaling pathways rather than broad immune suppression. Therefore, methotrexate is the csDMARD example.

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