Which corticosteroid is considered short-acting?

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Multiple Choice

Which corticosteroid is considered short-acting?

Explanation:
Short-acting corticosteroids are those whose anti-inflammatory effect lasts for the shortest time. Hydrocortisone fits this category, with activity lasting roughly 8–12 hours after systemic administration. This makes it the best choice when a shorter duration of action is desired or when physiologic replacement is needed, since it mirrors natural cortisol with some mineralocorticoid activity. In contrast, dexamethasone and betamethasone are long-acting, typically exerting effects for more than 36 hours, while methylprednisolone is intermediate-acting, usually around 12–36 hours.

Short-acting corticosteroids are those whose anti-inflammatory effect lasts for the shortest time. Hydrocortisone fits this category, with activity lasting roughly 8–12 hours after systemic administration. This makes it the best choice when a shorter duration of action is desired or when physiologic replacement is needed, since it mirrors natural cortisol with some mineralocorticoid activity. In contrast, dexamethasone and betamethasone are long-acting, typically exerting effects for more than 36 hours, while methylprednisolone is intermediate-acting, usually around 12–36 hours.

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