What kind of NSAIDs are recommended for all forms OA?

• A. Oral
• B. Topical
• C. Transdermal
• D. Intravenous

Answer: (A)

Oral NSAIDs are preferred because they deliver the medicine systemically, providing pain relief and anti-inflammatory effects across multiple joints. Osteoarthritis can affect various joints, and a single systemic dose helps address pain wherever it occurs by lowering prostaglandin synthesis through COX inhibition. Topical NSAIDs work best for superficial, localized joints and may not reach deeper joints like the hip or large joints as effectively, so they’re not universally adequate for all forms of OA. Intravenous NSAIDs aren’t used for long-term OA management, and transdermal options have variable absorption and are not the standard across all joint sites. Therefore, oral administration is the most broadly applicable choice for OA pain control.