Sarilumab is dosed at which regimen?

• A. 200 mg SQ every other week
• B. 100 mg weekly
• C. 400 mg monthly
• D. 50 mg IM every 2 weeks

Answer: (A)

Sarilumab dosing relies on delivering a steady, effective level of the drug through a convenient schedule. The approved regimen for rheumatoid arthritis is 200 mg given by subcutaneous injection every two weeks. This schedule provides consistent IL-6 receptor blockade to control symptoms while balancing safety and practicality for patients.

Other options don’t match how the drug is labeled or how it’s administered. A weekly 100 mg schedule would alter total exposure and isn’t the approved plan. A 400 mg monthly dose would leave longer gaps between treatments, reducing consistent receptor inhibition. An intramuscular route at 50 mg every two weeks isn’t how this medication is dosed or delivered.