Leflunomide is an example of which DMARD category?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the Dermatology Week 1 Exam with comprehensive study materials. Practice with detailed questions, flashcards, and expert explanations. Boost your knowledge and confidence for the exam!

Multiple Choice

Leflunomide is an example of which DMARD category?

Explanation:
Leflunomide is a conventional synthetic DMARD. These are small-molecule drugs taken orally that aim to modify the disease process in inflammatory arthritis. Leflunomide works by inhibiting dihydroorotate dehydrogenase, reducing de novo pyrimidine synthesis, and thereby decreasing the proliferation of activated T and B cells. This disease-modifying effect places it with other csDMARDs rather than biologic DMARDs (which are large protein drugs like monoclonal antibodies) or targeted synthetic DMARDs (which inhibit specific signaling pathways such as JAK inhibitors). NSAIDs, in contrast, mainly provide symptom relief without altering disease progression.

Leflunomide is a conventional synthetic DMARD. These are small-molecule drugs taken orally that aim to modify the disease process in inflammatory arthritis. Leflunomide works by inhibiting dihydroorotate dehydrogenase, reducing de novo pyrimidine synthesis, and thereby decreasing the proliferation of activated T and B cells. This disease-modifying effect places it with other csDMARDs rather than biologic DMARDs (which are large protein drugs like monoclonal antibodies) or targeted synthetic DMARDs (which inhibit specific signaling pathways such as JAK inhibitors). NSAIDs, in contrast, mainly provide symptom relief without altering disease progression.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy