Infliximab is an example of which DMARD type?

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Multiple Choice

Infliximab is an example of which DMARD type?

Explanation:
Biologic DMARDs are therapies derived from living organisms that target specific parts of the immune system, often a cytokine or its receptor. Infliximab is a biologic DMARD because it is a monoclonal antibody that binds tumor necrosis factor-alpha (TNF-α), blocking its inflammatory effects. This targeted approach contrasts with conventional synthetic DMARDs, which are small-molecule drugs with broader immune-suppressive actions. For example, methotrexate acts mainly as an antimetabolite with anti-proliferative effects, hydroxychloroquine modulates immune activation, and leflunomide inhibits pyrimidine synthesis. So infliximab belongs to the biologic DMARD category, while methotrexate, hydroxychloroquine, and leflunomide are conventional synthetic DMARDs.

Biologic DMARDs are therapies derived from living organisms that target specific parts of the immune system, often a cytokine or its receptor. Infliximab is a biologic DMARD because it is a monoclonal antibody that binds tumor necrosis factor-alpha (TNF-α), blocking its inflammatory effects. This targeted approach contrasts with conventional synthetic DMARDs, which are small-molecule drugs with broader immune-suppressive actions. For example, methotrexate acts mainly as an antimetabolite with anti-proliferative effects, hydroxychloroquine modulates immune activation, and leflunomide inhibits pyrimidine synthesis. So infliximab belongs to the biologic DMARD category, while methotrexate, hydroxychloroquine, and leflunomide are conventional synthetic DMARDs.

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