Infliximab, brand Remicade, is dosed by intravenous infusion at which rate per kilogram?

• A. Remicade IV 5 mg/kg
• B. Remicade SQ 50 mg weekly
• C. Cimzia IV 5 mg/kg
• D. Humira IV 5 mg/kg

Answer: (A)

Infliximab is a monoclonal antibody given by intravenous infusion, with dosing calculated based on patient body weight. The standard dose for each infusion is 5 mg per kilogram of body weight, typically given on a schedule that starts with three infusions (at weeks 0, 2, and 6) for induction and then every 8 weeks for maintenance. This makes the per-kilogram dose clear: 5 mg for every kilogram the patient weighs.

Remicade is delivered only by IV infusion; it is not given subcutaneously. The other options misstate either the route or the drug: a subcutaneous formulation is used for other TNF inhibitors, and Cimzia and Humira are not IV infusions of infliximab. Therefore, the correct description is Remicade given IV at 5 mg/kg.